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Online resource on advances in using genetic testing for improved biopsy decisions in the diagnosis of prostate cancer. 36 онкоурология экспериментальная и клиническая урология №2 2014 www.ecuro.ru Российская тест-система РСА3: первые результаты Russian PCA3 test-system: first results A.V. Sidorenkov, A.V. Govorov, D.Yu. The PCA3 test is a new type of test that may help to diagnose prostate cancer. There is information below about. The prostate cancer gene 3 (PCA3) urine test in men with previous negative biopsies: does free-to-total prostate-specific antigen ratio influence the performance of the PCA3 score in predicting positive biopsies? Early studies of the urinary PCA3 gene test indicate this new marker has a much greater degree of CaP specificity than PSA testing. PCA3 is only expressed in human prostate tissue, and the gene is highly overexpressed in prostate cancer.[1][2] Because of its restricted expression profile, the PCA3 RNA is useful as a tumor marker.[3]. PCA3 Test. The PCA3 test involves a digital rectal examination of the prostate and collection of sample of urine, which is taken for testing for the PCA3 gene. The performance of the PCa antigen 3 (PCA3) gene as a primary diagnostic is unknown. Objective: Assess the value of PCA3 as a rst-line diagnostic test. Design, setting and participants: Participants included men aged... What is the PCA3 score? This is a new genetic test that determines whether products of genes associated with prostate cancer are present in the urine of men. The Prostate CAncer gene 3 (PCA3) Assay is a gene-based test. It is not a replacement for prostate specific antigen (PSA). It is an additional tool to help decide if in men suspected of having prostate cancer (PCa), e.g. those with a PSA between 2.5 and 10 ng/mL... Информация взята v3.kz |
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